Pravastatin sodium salt hydrate ≥98% (HPLC), powder ยี่ห้อ Sigma

PROPERTIES

biological source

synthetic (organic)

Quality Level

100

Assay

≥98% (HPLC)

form

powder

color

white

mp

171.2-173 °C

solubility

H2O: >10 mg/mL

originator

Bristol-Myers Squibb

storage temp.

2-8°C

SMILES string

[Na+].[H][C@@](O)(CC[C@H]1[C@@H](C)C=CC2=C[C@@H](O)C[C@H](OC(=O)[C@@H](C)CC)[C@]12[H])C[C@@H](O)CC([O-])=O

InChI

1S/C23H36O7.Na/c1-4-13(2)23(29)30-20-11-17(25)9-15-6-5-14(3)19(22(15)20)8-7-16(24)10-18(26)12-21(27)28;/h5-6,9,13-14,16-20,22,24-26H,4,7-8,10-12H2,1-3H3,(H,27,28);/q;+1/p-1/t13-,14-,16+,17+,18+,19-,20-,22-;/m0./s1

InChI key

VWBQYTRBTXKKOG-IYNICTALSA-M

Gene Information

human ... HMGCR(3156)

DESCRIPTION

General description

Pravastatin sodium is an orally effective hypocholesterolaemic agent which is structurally similar to lovastatin and compactin.[1]

Application

Pravastatin sodium salt hydrate has been used in the enzymatic method to measure mevalonic acid in serum.[2]

Biochem/physiol Actions

Pravastatin sodium is a competitive, water-soluble 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor.[1]

Competitive, water-soluble 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Inhibits cholesterol synthesis in vivo (Ki ~1 nM).

Features and Benefits

This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

SAFETY INFORMATION

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable