Sodium oxamate ≥98% ยี่ห้อ Sigma

PROPERTIES

biological source

synthetic (organic)

Quality Level

200

Assay

≥98%

form

powder

mp

300 °C

solubility

water: 50 mg/mL, clear, colorless

SMILES string

[Na+].NC(=O)C([O-])=O

InChI

1S/C2H3NO3.Na/c3-1(4)2(5)6;/h(H2,3,4)(H,5,6);/q;+1/p-1

InChI key

RQVZIJIQDCGIKI-UHFFFAOYSA-M

DESCRIPTION

Application

Sodium oxamate has been used:

as one of the variable in flow injection analysis[1]

in in vitro angiogenesis assay[2]

to confirm the stimulatory role of stearic acid on lactate dehydrogenase mediated lactate production[3]

Biochem/physiol Actions

Sodium oxamate influences the fatty acid metabolism.[4] It might be useful for the treatment of diabetes.[5]

Structural analog of pyruvate, inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway[6]. Binding studies with lactate dehydrogenase[7]; Mechanism of inhibition of mitochondrial pyruvate metabolism[8]

SAFETY INFORMATION

Storage Class Code

11 - Combustible Solids

WGK

WGK

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable