Glycine Assay Kit (Fluorometric), ยี่ห้อ Sigma

PROPERTIES

detection method

fluorometric

storage temp.

−20°C

DESCRIPTION

General description

Glycine (GLY) is a non-essential amino acid used to help create muscle tissue and convert glucose into energy. It′s basic functions include the participation in the synthesis of creatine, glutathione, heme groups, and conjugated bile acids (bile salts). It is also used in the synthesis of DNA and RNA. It is one of the most abundant residues in the triple-helical structure of collagen, which contributes to the elasticity of skin and connective tissue. It acts as a glucogenic amino acid regulating blood sugar levels. Glycine is necessary for central nervous system function. It possesses both inhibitory and excitatory neurotransmitter functions in the brain stem and spinal cord. Recent studies suggest, glycine may play a role in tumorigenesis and malignancy. Some of the external sources of glycine includes legumes, meat, fish and dairy products.

Features and Benefits

Compatible with high-throughput handling systems.

Suitability

Suitable for the detection of glycine in biological fluids such as serum, plasma, saliva, urine, etc

Principle

The Glycine Assay Kit is a simple and reliable, high throughput assay that detects the physiological concentration of glycine in a variety of biological fluids. In the assay, glycine is oxidized generating a fluorometric (lex = 535 nm/ lem = 587 nm) product, proportional to the glycine present. The assay is specific, and other standard and non-standard amino acids do not interfere with the assay. The kit is sensitive to 1 mM of glycine.