d-(+)-Glucose Hybri-Max™, powder, BioReagent, suitable for hybridoma ยี่ห้อ Sigma

PROPERTIES

biological source

maize

Quality Level

200

grade

Hybri-Max™

product line

BioReagent

Assay

≥99.5%

form

powder

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

mp

150-152 °C (lit.)

solubility

H2O: 2g + 15 mL, clear, colorless

SMILES string

OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1

InChI key

WQZGKKKJIJFFOK-DVKNGEFBSA-N

Gene Information

human ... PYGM(5837)

DESCRIPTION

General description

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively.[1] The PYGM gene is mapped to human chromosome 11q13.1.[2]

Application

D-(+)-Glucose has been used in cell engineering.[3] It has also been used to perform oral glucose tolerance test.[4]

Biochem/physiol Actions

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia.[1] Mutation in PYGM leads to McArdle disease, a glycogen storage disorder.[5] The PYGM gene is significantly associated with energy production.[6]

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

SAFETY INFORMATION

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves